By E. Molinari, A. Compare, G. Parati

This comprehensve assessment of medical learn aiding proof of the connection among cardiac sickness and mental situation deals functional feedback for constructing a scientific perform, and proposes instructions for destiny study within the new box of "cardiac psychology". each bankruptcy is written via world-renowned researchers within the box. A theoretical and sensible advisor, it's going to curiosity physicians, medical and healthiness psychologists, and all execs who search to appreciate the mind-health hyperlink.

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The underlying mechanisms have a detrimental influence on the cardiovascular system not only through unfavorable lifestyle, but biological mechanisms as well (examples are endothelial damage and increased heart rate and blood pressure). People with hostile behavior also have increased plasma homocysteine [13]. Homocysteine is an amino acid derived from dietary methionine. Its levels are regulated through a complex interaction of genetic, dietary and hormonal factors, and it plays a role in the process or atherogenesis.

Dunbar F (1954) Emotions and bodily changes, 4th ed. New York: Columbia University Press 4. Dunbar F (1950) Psychosomatic medicine. In: Lorand S (Ed) Psychoanalysis today, 4th edition, New York: International University Press, pp 23-42 5. Kannel WB, Castelli WP, Gordon T, McNamara PM (1971) Serum cholesterol, lipoproteins, and the risk of coronary heart disease. The Framingham Study. Ann Intern Med 74:1-12 6. Haynes SG, Feinleib M, Kannel WB (1980) The relationship of psychosocial factors to coronary heart disease in the Framingham study: III.

G. g. diabetes, heart disease, high blood pressure). Chapter 2 - Psychological Risk Factors for Cardiac Disease 23 ■ Brief Overview of the Biological Mechanisms Underlying the Pathogenesis of Ischemic Heart Disease It is useful to define a framework within which to understand the complex interactions between body and mind in the pathogenesis of ischemic heart disease. CHD is almost always secondary to an obstruction of the flow in the coronary arteries due to atherosclerosis. We still do not have a satisfactory knowledgebase of the early phases of atherosclerosis, but they are probably characterised by the accumulation of lipids in the internal layer of the artery called intima.

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