By John Henderson
Ernest Starling (1866-1927) was once pre-eminent within the golden age of British body structure. His identify is mostly linked to his "Law of the Heart," yet his discovery of secretin (the first hormone whose mode of motion used to be defined) and his paintings on capillaries have been extra very important contributions. He coined the notice 'hormone' 100 years in the past. His research of capillary functionality validated that equivalent and contrary forces stream around the capillary wall--an outward (hydrostatic) strength and an inward (osmotic) strength derived from plasma proteins. Starling's contributions include:*Developing the "Frank-Starling legislations of the Heart," offered in 1915 and changed in 1919.*The Starling equation, describing fluid shifts within the physique (1896) *The discovery of secretin, the 1st hormone, with Bayliss (1902) and the advent of the concept that of hormones (1905).
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Additional resources for A Life of Ernest Starling (People and Ideas Series)
The vigor with which the student Starling defended his views is absolutely characteristic; speaking his mind was already a strength and a weakness in his character. An important influence at this time was his friend Leonard Wooldridge (1857-1889), a young physiologically oriented Guy's physician. Wooldridge had a star-studded academic career through Guy's, and in 1879 went to Leipzig, where he worked for a year with Carl Ludwig, the leading Ger- Hearts and Capillaries 17 Figure 1-3. Ernest Starling, photographed in Germany, aged about twenty.
I shall be delighted to do so if I can possibly arrange i t . . I have, however, written to Golding-Bird, who, as senior, has the choice 30 A Life of Ernest Starling of times, to ask him to let me lecture for the first 6 weeks, from the first of October. If he consents, there will be no difficulty at all. I will let you know as soon as I hear from him . . With kind regards, in which my wife joins Ernest H. StarUng S a n d e r s o n h a d p r e s u m a b l y h e a r d Starling speak at t h e Physiological Society.
H e went for h e l p to Professor Edward Schafer at University College. This is the earliest Starling letter that has survived (Starling, 1891). Dear Professor Schafer May 21, 1891 I am glad to say that I was partially successful in the matter of lectureships. The Guy's staff could not make up their minds between Washbourn and myself, so they appointed us both. As GoldingBird only gives up to one fourth of the lectures, Washbourn and I each take one eighth. It is a rather ridiculous arrangement, but I suppose the title of Joint Lecturer will be useful to me—at least I hope it will.